HIGHLIGHTS
- who: Lipid oligonucleotides as a and colleagues from the University of have published the research work: tackling the antibiotic resistance, in the Journal: Scientific Reports Scientific Reports of 18/03/2019
- what: The aim of this study was to enlarge the self-delivery concept of therapeutic oligonucleotides for antibiotherapy purpose, to tackle the antibiotic resistance issue. To validate the approach , a family of oligonucleotide conjugates was investigated with ceftriaxone as a β-lactam antibiotic. β-lactam, including penicillins, cephalosporins, carbapenems and monobactam are the most used antibiotics for the treatment of bacterial infections12. The experiments show that . . .
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