HIGHLIGHTS
- who: PR- and collaborators from the Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, School of Life Sciences, University of Dundee, Dundee , EH, UK have published the research: Restoring Tumour Selectivity of the Bioreductive Prodrug PR-104 by Developing an Analogue Resistant to Aerobic Metabolism by Human Aldo-Keto 1C3, in the Journal: (JOURNAL)
- what: The authors report a novel analogue of PR-104A for which the authors have designed out metabolic activation by human AKR1C3. In the present work, a more direct three-step procedure was developed that has . . .
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