A threshold of endogenous stress is required to engage cellular response to protect against mutagenesis endogenous stress represents major source of genome instability but is in essence difficult to apprehend

HIGHLIGHTS

• who: Yannick Saintigny and colleagues from the Institut have published the research work: A threshold of endogenous stress is required to engage cellular response to protect against mutagenesis Endogenous stress represents major source of genome instability but is in essence difficult to apprehend, in the Journal: Scientific Reports Scientific Reports
• what: The authors demonstrate that thymidine generates oxidative stress and oxidative damage-induced mutagenesis. Incorporation of_[3H]thymidine can generate ROS through water radiolysis, and the authors show here that incorporation of_[3H]thymidine actually increases the level of endogenous | 6:29412 | DOI: 10.1038 . . .
  

   

  

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