Biology using lanthanoid complexes to phase large macromolecular assemblies

HIGHLIGHTS

  • who: TET aminopeptidase. and collaborators from the CEA, IBS, France, bCNRS, UMR5075, France, cUniversité have published the article: biology Using lanthanoid complexes to phase large macromolecular assemblies, in the Journal: (JOURNAL)
  • what: The authors report the use of the tris-dipicolinate complex to obtain experimental phases at low resolution on a large homododecameric enzyme, PhTET1-12s, which is a tetrahedral aminopeptidase belonging to a new family of self-compartmentalized large protease complexes . The authors show that low-resolution experimental phase obtained with tris-dipicolinate complex can provide novel structural information on the PhTET1-12s complex . . .

     

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