An electrostatic switching mechanism to control the lipid transfer activity of osh6p

HIGHLIGHTS

• who: Nicolas-Frédéric Lipp et al. from the CNRS have published the research work: An electrostatic switching mechanism to control the lipid transfer activity of Osh6p, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
• what: The authors demonstrate that a LTP uses an electrostatic switching mechanism to self-limit its residency time on membranes and thereby, be efficient.
• how: Jointly these data indicated that Osh6pΔ69 and Osh6p(L69D) extract neither PS nor PI4P whereas Osh6p(HH/AA) is still able to encapsulate PS. Comparable results were obtained with diphytanoyl-PS-rich . . .
  

   

  

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