HIGHLIGHTS
- who: Neo et_al BMC Cancer and colleagues from the Department of Surgery, The University of Melbourne, Austin Health, Heidelberg, Victoria, Australia have published the research work: Open Access, in the Journal: (JOURNAL)
- what: This model has been characterized previously and results in metastases exclusively confined to the liver . The authors found that AT1R expression was lower in CRC metastases compared to the surrounding liver. This study provides evidence of a complete local RAS in both the normal and tumor-bear- ing mouse liver. The authors show a marked up-regulation of ACE during CRC metastases . . .
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