Hepatic lipocalin 2 promotes liver fibrosis and portal hypertension

HIGHLIGHTS

• who: Jiegen Chen from the DepartmentsUniversity of have published the Article: Hepatic lipocalin 2 promotes liver fibrosis and portal hypertension, in the Journal: Scientific Reports Scientific Reports
• what: The authors provide evidence that LCN2 is massively overexpressed in the liver from patients with AH and its expression correlates with the degree of fibrosis and portal hypertension. The authors focused the analysis on Canonical Pathway gene sets, from Curated Gene Sets ­collection51.
• how: Even in the absence of overt fibrosis in this model (Supplementary Figure 3a) the authors found that Timp1 expression an important . . .
  

   

  

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