HIGHLIGHTS
- who: Qingnuan Kong from the (UNIVERSITY) have published the Article: Conditional Dnmt3b deletion in hippocampal dCA1 impairs recognition memory, in the Journal: (JOURNAL)
- what: The authors aim to explore the role of DNMT3b and its-mediated DNA methylation in processes.
SUMMARY
That DNA methylation alterations in brain neurons dynamically modulates synaptic plasticity and are required for multiple forms of memory formation, for example contextual fear memory, object recognition memory, and spatial memory. EPO micro-injected into the hippocampus upregulated Dnmt3b expression and improved spatial learning and amp; memory in SAMP8 mice . . .
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