Defective excitatory/inhibitory synaptic balance and increased neuron apoptosis in a zebrafish model of dravet syndrome

HIGHLIGHTS

  • who: Alexandre Brenet et al. from the (UNIVERSITY) have published the article: Defective Excitatory/Inhibitory Synaptic Balance and Increased Neuron Apoptosis in a Zebrafish Model of Dravet Syndrome, in the Journal: Cells 2019, 8, 1199 of /2019/
  • what: The authors focused on excitatory and inhibitory synapses by studying two important proteins that are markers of synaptic integrity, PSD-95 and gephyrin . The authors demonstrated that levels of PSD-95 and gephyrin are modified in zebrafish models of DS. The study shows that DS is a disease of the central nervous system, and it calls for . . .

     

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