Hiding in plain sight: virtually unrecognizable memory phenotype cd8+ t cells

HIGHLIGHTS

  • who: Daniel Thiele and collaborators from the Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University have published the article: Hiding in Plain Sight: Virtually Unrecognizable Memory Phenotype CD8+ T cells, in the Journal: (JOURNAL)
  • what: In this study, it was demonstrated that, in the absence of DOT1L from T_cells, almost all CD8+ T_cells exhibited a TVM cell phenotype.
  • how: The study indicates that there is no difference in basal mitochondrial characteristics such as mitochondrial mass and number of mitochondria per cell between TVM cells compared to other CD8+ subsets .
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