The mitochondrial genome in aging and disease and the future of mitochondrial therapeutics

HIGHLIGHTS

  • who: Sanjana Saravanan and colleagues from the Division of Mitochondria Biology, SENS Research Foundation, Pioneer Way, Suite J, Wolfson School of Mechanical, Electrical and Manufacturing Engineering, Loughborough University, Loughborough , TU, UK have published the research: The Mitochondrial Genome in Aging and Disease and the Future of Mitochondrial Therapeutics, in the Journal: Biomedicines 2022, 10, 490. of 18/02/2022
  • what: This approach has limitations in that the acquired mutation must harbor a specific restriction site to distinguish mutant and wild-type mtDNA copies, and efficiently introducing restriction enzymes into target cells and into mitochondria still . . .

     

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