HIGHLIGHTS
- who: Richard T. Timms from the Biology, University of Copenhagen, Copenhagen N, Denmark, Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Cambridge , SA have published the paper: Genetic dissection of mammalian ERAD through comparative haploid and CRISPR forward genetic screens, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 10/06/2016
- what: The authors compare the efficacy of genome-wide CRISPR/Cas9-mediated screens versus gene-trap mutagenesis screens in haploid human cells which represent the existing ‘gold standard' method. Both screens also identify a role for the uncharacterized gene TXNDC11 which the authors show . . .
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