Pkd2l1 is required for mechanoception in cerebrospinal uid-contacting neurons and maintenance of spine curvature

HIGHLIGHTS

• who: Jenna R. Sternberg et al. from the UniversitéResearch University of Medical Science, Tokushima, Japan have published the article: Pkd2l1 is required for mechanoception in cerebrospinal uid-contacting neurons and maintenance of spine curvature, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 20/08/2018
• what: The authors investigate flow of the CSF within the spinal cord, detection of flow by CSF-cNs, and how altered flow can lead to spinal defects. Using calcium imaging, the authors show that ventral CSF-cNs in this mutant lose spontaneous activity in_vivo. The authors demonstrate that Pkd2l1 . . .
  

   

  

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