Structures of the human pals1 pdz domain with and without ligand suggest gated access of crb to the pdz peptide-binding groove

HIGHLIGHTS

• who: PDB references PDZ-peptide complex and collaborators from the Molecular Biology, Department of Biological Sciences, Birkbeck College, University of London, Malet Street have published the research work: Structures of the human Pals1 PDZ domain with and without ligand suggest gated access of Crb to the PDZ peptide-binding groove, in the Journal: (JOURNAL)
• what: This study characterizes the carboxy-terminal (ERLI) motif of Crb, which is crucial in_vivo for polarity and binds to Pals1/ Stardust. The authors show that deleting the PDZ-binding ERLI motif from fly Crb results in disrupted Crb polarization in . . .
  

   

  

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