Mechanical force-induced morphology changes in a human fungal pathogen

HIGHLIGHTS

• who: Charles Puerner from the (UNIVERSITY) have published the Article: Mechanical force-induced morphology changes in a human fungal pathogen, in the Journal: (JOURNAL)
• what: The authors show that there is a threshold for penetration that corresponds to a stiffness of ~ 200 kPa and that invasive growth within a stiff substrate is characterized by dramatic filament buckling along with a stiffness-dependent decrease in extension rate. Analysis, the authors determined the effective turgor pressure (ΔP=P - Pc) to be 1.5 and 3.1 MPa, in 100 kPa and 150 kPa PDMS, respectively.
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