The guanosine tetraphosphate (ppgpp) alarmone, dksa and promoter affinity for rna polymerase in regulation of σ54-dependent transcription

HIGHLIGHTS

• who: Yormiar from the DepartmentUmeå University have published the research: The guanosine tetraphosphate (ppGpp) alarmone, DksA and promoter affinity for RNA polymerase in regulation of σ54-dependent transcription, in the Journal: (JOURNAL)
• what: The authors propose a passive model for ppGpp/DksA regulation of s54-dependent transcription that depends on potent negative effects of these regulatory molecules on transcription from powerful stringently regulated s70 promoters. The experiment shown in Fig 4 compares the ability of increasing concentrations of σ54 to compete with 20 nM σ70 for 10 nM core RNAP in the presence or absence . . .
  

   

  

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