Certl reduces c16 ceramide, amyloid-β levels, and inflammation in a model of alzheimer’s disease

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  • who: Simone M. Crivelli from the Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Universiteitssingel, ER Maastricht, the Netherlands have published the research: CERTL reduces C16 ceramide, amyloid-β levels, and inflammation in a model of Alzheimer’s disease, in the Journal: (JOURNAL)
  • what: The authors report that binds to APP modifies Aβ aggregation and Aβ neurotoxicity in vitro. The authors show that intracortical injection of mediating the expression of decreases levels of d18:1/16:0 and increases levels in the brain of male 5xFAD mice. in vivo overexpression has . . .

     

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