HIGHLIGHTS
- who: Danièle Noël from the France, University, UFR de Médecine, France have published the research: Thrombospondin-1 Partly Mediates the Cartilage Protective Effect of Adipose-Derived Mesenchymal Stem Cells in Osteoarthritis, in the Journal: (JOURNAL)
- what: The authors showed that rTHBS1 exerted an anti-proliferative role on T lymphocytes and that downregulation of THBS1 in ASCs decreased their immunosuppressive activity which could be related to lower expression of the immunosuppressive enzyme IDO1.
- how: Among differentially secreted proteins induced in coculture the authors identified thrombospondin-1 (THBS1) as a potential candidate . . .
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