Low doses of ionizing radiation promote tumor growth and metastasis by enhancing angiogenesis

HIGHLIGHTS

• who: Inês Sofia Vala and colleagues from the Angiogenesis Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal, Cancer Biology Unit, Instituto de Medicina have published the paper: Low Doses of Ionizing Radiation Promote Tumor Growth and Metastasis by Enhancing Angiogenesis, in the Journal: (JOURNAL) of June/21,/2010
• what: The authors show that low-dose IR induces a rapid phosphorylation of several endothelial cell proteins including the Vascular Endothelial Growth Factor (VEGF) Receptor-2 and induces VEGF production in hypoxia mimicking conditions. Using murine experimental models of leukemia . . .
  

   

  

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