HIGHLIGHTS
- who: Pauline Jacquet from the (UNIVERSITY) have published the research: Rational engineering of a native hyperthermostable lactonase into a broad spectrum phosphotriesterase, in the Journal: (JOURNAL) of 29/08/2017
- what: The authors focus on the molecular engineering of an enzymatic bio-decontaminant of organophosphates compounds (OPs), including nerve agents and insecticides. The authors aimed to further improve the phosphotriesterase activity of SsoPox, including against phosphothionoesters.
- how: The authors used a rational strategy taking advantage of the structural similarity between SsoPox and the bacterial PTE from the mesophilic Brevundimonas diminuta (BdPTE)27 the . . .
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