HIGHLIGHTS
- who: Michael Crompton and collaborators from the Department of Surgical Sciences, University of Oxford, Oxford, Oxfordshire, United have published the article: A mutation in Nischarin causes otitis media via LIMK1 and NF-κB pathways, in the Journal: (JOURNAL) of May/27,/2017
- how: The authors identified and characterised edison a novel mouse model of chronic OM that shares important features with the chronic disease in humans. Il1b (15-fold t-test p=0.003) and Tnfa (66-fold t-test p and amplt 0.001) are known modulators of Hif1a translation and expression data indicated . . .
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