Anti-migratory effect of vinflunine in endothelial and glioblastoma cells is associated with changes in eb1 c- terminal detyrosinated/tyrosinated status

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  • who: Amandine Rovini et al. from the Institut de Pierre Fabre, Toulouse, FranceEditor: Yulia Komarova, University of Illinois at Chicago, United States of America have published the paper: Anti-Migratory Effect of Vinflunine in Endothelial and Glioblastoma Cells Is Associated with Changes in EB1 C- Terminal Detyrosinated/Tyrosinated Status, in the Journal: PLOS ONE | www.plosone.org of September/25,/2012
  • what: The authors first showed that the pro-angiogenic vascular endothelial growth factor VEGF suppressed microtubule dynamics in living Human Umbilical Vein Endothelial Cells (HUVECs) increased EB1 comet length by 40% and induced EB1 . . .

     

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