HIGHLIGHTS
- who: T. Secher and collaborators from the Molecular Immunology and Embryology, University of Orleans and CNRS, Orleans, France have published the research work: Enhancement of Methacholine-Evoked Tracheal Contraction Induced by Bacterial Lipopolysaccharides Depends on Epithelium and Tumor Necrosis Factor, in the Journal: (JOURNAL) of 28/Nov/2011
- what: This study examined the effect of LPS on contractile airway responses. This study showing both TLR4 and tracheal epithelium requirement together with the TLR4-LPS interaction suggests that the LPSinduced hyperreactivity involves epithelial_cells expressing TLR4. The authors report that LPS activates TLR4 on epithelial_cells of the . . .
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