Phthalimide derivative shows anti-angiogenic activity in a 3d microfluidic model and no teratogenicity in zebrafish embryos

HIGHLIGHTS

• who: Andrea Pavesi and Giulia Adriani from the Galgotias University, India have published the article: Phthalimide Derivative Shows Anti-angiogenic Activity in a 3D Microfluidic Model and No Teratogenicity in Zebrafish Embryos, in the Journal: (JOURNAL)
• how: The concentrations tested for C4 were much lower than the concentrations tested for Thalidomide because the authors observed in the in_vitro experiments that C4 was very effective already at a concentration of 0.5 µM thus the authors decided to further reduce its concentration in the in_vivo treatment.
• future: Lenalidomide and Pomalidomide were Frontiers in Pharmacology . . .
  

   

  

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