A nonsynonymous mutation in plcg2 reduces the risk of alzheimer’s disease, dementia with lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

HIGHLIGHTS

  • who: Sven J. van der Lee from the (UNIVERSITY) have published the article: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity, in the Journal: (JOURNAL)
  • what: The authors used maternal and paternal history of Alzheimer's/dementia as proxy for dementia and the reported age of the parents (at completing the survey or death) as proxy phenotype for longevity . In this analysis, the authors compared 35,256 UK Biobank participants who had a mother who reached at least . . .

     

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