Reversing blood flows act through klf2a to ensure normal valvulogenesis in the developing heart

HIGHLIGHTS

  • who: Gharib, and Scott E., Fraser from the Institute of Technology, Pasadena, California, United States of America, Electrical and Computer Engineering, University of California Santa Barbara, Santa Barbara have published the research: Reversing Blood Flows Act through klf2a to Ensure Normal Valvulogenesis in the Developing Heart, in the Journal: (JOURNAL) of November/17,/2009
  • what: By manipulating blood flow patterns, the authors show that reversing flows are essential for valve morphogenesis. Using antisense morpholine oligonucleotides (MOs) and drugs to alter these flow patterns in zebrafish, the authors show that reversing flow is essential to trigger . . .

     

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