HIGHLIGHTS
- who: Benjamin B. Williams and colleagues from the 052, AustraliaDepartment Medical Biology, University have published the Article: Glycoprotein A33 deficiency: a new mouse model of impaired intestinal epithelial barrier function and inflammatory disease, in the Journal: (JOURNAL)
- what: Implications and future directions This study shows a non-redundant role for GPA33 in the maintenance of intestinal barrier function. The ease with which Gpa33-/- mice can be manipulated to elicit a suite of intestinal pathologies, including loss of oral tolerance, severe colitis and CAC, suggests that this model might provide an attractive option for preclinical studies . . .
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