HIGHLIGHTS
- who: Marcos Rayel from the (Alves et_al, )p, is a tumor suppressor gene located on chromosome, and the protein it codes acts on cell growth, DNA repair and synthesis, cell differentiation and apoptosis. The functional inactivation of p, is one of the most common alterations in various neoplasms. The mutations lead to alterations of the coded proteins, which start showing a higher half-life, accumulate in neoplastic cells, and can be detected by immunohistochemical technique (Suzano, ). In view of all this, it can be noted that there are few scientific studies corroborating the antitumoral properties of E . . .
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