HIGHLIGHTS
- who: Eve Duchemin-Pelletier and collaborators from the Biology of Cancer and Infection, UMRS1036, Inserm, Grenoble, France have published the paper: Stem Cell-Like Properties of CK2-down Regulated Mammary Cells, in the Journal: Cancers 114 Analysis of2017, Cell9, Phenotypes by Orthotopic Engraftment of /2017/
- what: Through transcriptomic and miRNA analysis together with comparison of cellular properties between wild type and CK2β-knock-down MCF10A cells the authors show that down-regulation of CK2β subunit in mammary epithelial cells induces the acquisition of stem cell-like properties associated with perturbed polarity CD44high /CD24low antigenic phenotype . . .
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