Atr contributes more than atm in intra-s-phase checkpoint activation after ir, and dna-pkcs facilitates recovery: evidence for modular integration of atm/atr/dna-pkcs functions

HIGHLIGHTS

  • who: Aashish Soni and collaborators from the Division of Experimental Radiation Biology, Department of Radiation Therapy, University Hospital Essen, and Research Center (DKFZ), Essen, Germany have published the article: ATR Contributes More Than ATM in Intra-S-Phase Checkpoint Activation after IR, and DNA-PKcs Facilitates Recovery: Evidence for Modular Integration of ATM/ATR/DNA-PKcs Functions, in the Journal: (JOURNAL)
  • what: Specifically, the authors investigate the mutual interactions and dependencies among ATM, ATR, and DNA-PKcs in the regulation of this checkpoint. The authors report that in contrast to the G2 checkpoint response of . . .

     

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