Using drosophila melanogaster to analyse the human paralogs of the escrt-iii core component shrub/chmp4/snf7 and its interactions with members of the lgd/cc2d1 family

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  • who: Miriam Baeumers et al. from the Institute of Genetics, Heinrich-Heine-Universitaet Duesseldorf, Universitaetsstr, have published the research: Using Drosophila melanogaster to Analyse the Human Paralogs of the ESCRT-III Core Component Shrub/CHMP4/Snf7 and Its Interactions with Members of the LGD/CC2D1 Family, in the Journal: (JOURNAL)
  • what: The authors provide evidence that the CHMP4B is the true functional ortholog of Shrub and that CHMP4A and C have partially divergent functions. This study showed that the AAs identified for Shrub protomer interactions are also important for the activity of CHMP4B, with one . . .

     

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