An integrated atlas of human placental development delineates essential regulators of trophoblast stem cells

HIGHLIGHTS

  • who: from the Datasets inclusion criteria were: (1) the scRNA-seq was performed on the Smart-seq, platform have published the Article: An integrated atlas of human placental development delineates essential regulators of trophoblast stem cells, in the Journal: (JOURNAL) of 12/05/2022
  • what: The authors determine the transcriptional networks of trophoblast lineages in vivo and leverage probabilistic modelling to identify a role for MAPK signalling in trophoblast differentiation.
  • how: To identify potential cell fate regulators the authors conducted differential gene_expression analysis of transcription factors between trophoblast subtypes (Fig 1F-H).
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