Inhibition of ppar a induces cell cycle arrest and apoptosis, and synergizes with glycolysis inhibition in kidney cancer cells

HIGHLIGHTS

  • who: Omran Abu Aboud et al. from the Division of Nephrology, Department of Internal Medicine, University of California Davis, Davis, California, United States of America, Comparative Pathology Graduate have published the Article: Inhibition of PPAR a Induces Cell Cycle Arrest and Apoptosis, and Synergizes with Glycolysis Inhibition in Kidney Cancer Cells, in the Journal: PLOS ONE | www.plosone.org of June/26,/2013
  • what: The authors provide evidence that when RCC cells are deprived of the glycolysis substrate, they become more sensitive to PPARa antagonists, suggesting that RCC cells alter their energy metabolism pathways under . . .

     

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