Grape seed and skin extract, a potential prebiotic with anti-obesity effect through gut microbiota modulation

HIGHLIGHTS

• who: Mohamed Mokrani from the Forty-eight male Wistar rats of , weeks old were obtained from Pasteur Institute Tunis, and housed in a controlled environment (, rats/cage) in agreement with the Local Ethics Committee of Carthage University that approved the experimental protocol and with NIH (National Research Council) guidelinesAfter one week of adaptation, rats were allocated into two groups fed either SD or HFD for three months (diets compositions Additional file, ). Then each group was divided into four subgroups (n=6) that were treated for three other months with GSSE (SDGSSE and HFGSSE), OR (SDOR and HFOR . . .
  

   

  

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