Preclinical pharmacology of a lipophenol in a mouse model of light-induced retinopathy

HIGHLIGHTS

• who: Nicolas Taveau from the IP-DHA was synthetized and purified as previously described IP-DHA-atRAL adducts were synthesized from isopropyl-phloroglucinol, as described in the supplemental material. DHA ethyl ester, generously gifted by Vincent Rioux (Agrocampus Ouest, Rennes, France), was purified using an n, polyunsaturated fatty acid (PUFA) marine oil (Omegavie EE Qualitysilver, Polaris) process, as described25. Emixustat hydrochloride was purchased from Ambinter (Amb24183355, GreenPharma Orleans). Fatty acid-free bovine serum albumin (BSA) was purchased from Sigma-Aldrich (#, ). AtRAL and alltrans-retinyl palmitate (atRPalm) standards were purchased from Sigma-Aldrich (# , and, respectively), whereas, cRAL was . . .
  

   

  

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