A 3d collagen-based bioprinted model to study osteosarcoma invasiveness and drug response

HIGHLIGHTS

  • who: Evelin Pellegrini and collaborators from the Laboratory of Experimental Oncology, IRCCS Istituto Ortopedico Rizzoli, Via di Barbiano, Bologna, Italy have published the Article: A 3D Collagen-Based Bioprinted Model to Study Osteosarcoma Invasiveness and Drug Response, in the Journal: Polymers 2022, 4070 of /2022/
  • what: The authors demonstrated that the 3D condition enhanced the expression of genes implicated in the repair of CDDP-induced DNA damages before OS cells were exposed to any chemotherapeutic drug, and decreased sensitivity to chemotherapeutic agents. The authors show that the 3D hydrogel provided a better structural support than . . .

     

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