A , b -d-constrained nucleic acids are strong terminators of thermostable dna polymerases in polymerase chain reaction

HIGHLIGHTS

• who: Reaction et al. from the 068, Centre National de la Scientifique, Toulouse, France have published the research work: a , b -D-Constrained Nucleic Acids Are Strong Terminators of Thermostable DNA Polymerases in Polymerase Chain Reaction, in the Journal: (JOURNAL) of June/11,/2010
• what: The authors were focused on a class of recently described nucleotides, the (SC59, RP) a,b-D-CNA TT (CNA).
• how: The results showed that the incorporation of only one CNA was always skipped by the polymerases tested. The authors used CNA to induce bending in the template . . .
  

   

  

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