HIGHLIGHTS
- who: Lina Liu from the (UNIVERSITY) have published the paper: A bacteria-based system expressing anti-TNF-u03b1 nanobody for enhanced cancer immunotherapy, in the Journal: (JOURNAL) of 15/08/2022
- how: These results indicated that VNPu03b1TNF-u03b1 mobilized the systemic immune_response.
SUMMARY
As a result, significant tumor apoptosis was induced from 15 to 25% by VNPαTNF-α-stimulated splenic T_cells (Fig 1r, s). Detection of relative expression of markers by RT-PCR showed that VNPαTNF-α induced CD8+ T_cell polarization into cytotoxic T_cells, according to the upregulated TNF-α, IFN-γ, IL . . .
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