HIGHLIGHTS
SUMMARY
Many studies in recent decades have confirmed that the GM contributes to the pathophysiology of CVD, and understanding the underlying mechanisms could provide novel therapeutic strategies for treating CVD (He et_al, 2015; Blandino et_al, 2016; Li et_al, 2017). Hypertension and dyslipidemia are two dominant risk factors for CVD and are related to the alteration of the GM (Li et_al, 2017; Chi et_al, 2019; Zwartjes et_al, 2021). The total number of these microorganisms in the microbiota is more than 10 trillion (Witkowski et_al, 2020; Ley, 2022). The GM releases endotoxins or metabolites that trigger the . . .
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