A bifurcation concept for b-lymphoid/plasmacytoid dendritic cells with largely fluctuating transcriptome dynamics

HIGHLIGHTS

  • who: Keiki Nagaharu from the Mie University of Medicine, Tsu, Japan have published the paper: A bifurcation concept for B-lymphoid/plasmacytoid dendritic cells with largely fluctuating transcriptome dynamics, in the Journal: (JOURNAL) of August/30,/2022
  • what: The authors provide a model of fluctuation-based differentiation which reconciles continuous and discrete models and is applicable to other developmental systems. By orchestrating biological and computational methods, this study proposes a paradigm of a cell differentiation model based on comprehensive genetic profiling and provides the potential for application to various developmental and differentiation systems.
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