A biomathematical model of atherosclerosis in mice

HIGHLIGHTS

  • who: Sibylle Schirm et al. from the Institute for Medical Informatics, Statistics and Epidemiology, University Leipzig, Leipzig, Germany have published the paper: A biomathematical model of atherosclerosis in mice, in the Journal: PLOS ONE of October/18,/2021
  • what: The authors aim to validate the model on the basis further experimental data. The authors develop an ordinary differential equations model of atherosclerotic plaque formation in mice describing the dynamics of relevant lipid species and immune cells in blood and atherosclerotic lesions and the impact of interventions thereon. The authors determined the parameter values by optimizing . . .

     

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