HIGHLIGHTS
- who: Byoungkwon Kim from the University of Genoa, Italy have published the article: A brief glimpse of a tangled web in a small world: Tumor microenvironment, in the Journal: (JOURNAL)
- what: Immune cells are still the major focus in the era of ICIs, and the classification systems based on proportion of these cells have been proposed .
- future: The current mini-review aims to cover as many attributes in this complex system ranging from ions to cell and extracellular matrix (ECM) to physico-chemical properties of TME in an attempt to assist future studies . . .

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