A cationic motif upstream engrailed2 homeodomain controls cell internalization through selective interaction with heparan sulfates

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  • who: Su00e9bastien Cardon from the (UNIVERSITY) have published the Article: A cationic motif upstream Engrailed2 homeodomain controls cell internalization through selective interaction with heparan sulfates, in the Journal: (JOURNAL) of 11/Nov/2021
  • what: Based on previous reports4 and the data in the present work, the authors propose that sulfated GAGs anchored by proteins at the cell surface would be good candidates as translocation initiators (Fig 5). Following this model, the authors propose that the bidirectional transfer of En2 is regulated by a dynamic equilibrium between protein-lipid or protein-GAG interactions depending on the . . .

     

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