A cell type-specific constitutive point mutant of the common ù²-subunit of the human granulocyte-macrophage colony-stimulating factor (gm-csf), interleukin (il)-3, and il-5 receptors requires the gm-csf receptor ù±-subunit for activation*

HIGHLIGHTS

• who: Brendan J. Jenkins from the (UNIVERSITY) have published the research: A Cell Type-specific Constitutive Point Mutant of the Common u00d9u00b2-Subunit of the Human Granulocyte-Macrophage Colony-stimulating Factor (GM-CSF), Interleukin (IL)-3, and IL-5 Receptors Requires the GM-CSF Receptor u00d9u00b1-Subunit for Activation*, in the Journal: (JOURNAL) of May/21,/1998
• what: The authors report here that one such molecule is the mouse GMRa (mGMRa) subunit, since introduction of mGMRa, but not hGMRa, into BAF-B03 or CTLL-2 cells expressing the I374N mutant conferred factor independence.
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