A clinically relevant polymorphism in the na+/taurocholate cotransporting polypeptide (ntcp) occurs at a rheostat position

HIGHLIGHTS

  • who: Melissa J. Ruggiero from the Melissa JRuggiero1, Shipra Malhotra2, Aron W. Fenton4, Liskin Swint-Kruse4, John Karanicolas2, and Bruno Hagenbuch1, * From the Department of Pharmacology, Toxicology and Therapeutics, The University of Kansas Medical Center, Kansas City, Kansas, USA have published the article: A clinically relevant polymorphism in the Na+/taurocholate cotransporting polypeptide (NTCP) occurs at a rheostat position, in the Journal: (JOURNAL) of June/18,/2020
  • what: The authors report a strong rheostat position in the integral_membrane_protein, Na+/taurocholate (TCA) cotransporting polypeptide, at the site of a pharmacologically relevant polymorphism (S267F).
  • how . . .

     

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