A co-transcriptional ribosome assembly checkpoint controls nascent large ribosomal subunit maturation

HIGHLIGHTS

• who: Zahra A. Sanghai from the Laboratory of Protein and Nucleic Acid Chemistry, The Rockefeller University, New York, New York, USA have published the research: A co-transcriptional ribosome assembly checkpoint controls nascent large ribosomal subunit maturation, in the Journal: (JOURNAL) of 13/Oct/2022
• what: The authors report the cryo-electron microscopy structure of the yeast co-transcriptional large ribosomal subunit assembly intermediate that serves as a checkpoint.

SUMMARY

The structure provides the mechanistic basis for how quality-control pathways are established through co-transcriptional ribosome assembly factors, that structurally . . .

 



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