A cohesin-based partitioning mechanism revealed upon transcriptional inactivation of centromere

HIGHLIGHTS

  • who: Michael Tsabar et al. from the Department of Biology and Rosenstiel Basic Medical Sciences Research Center, Brandeis University have published the research: A Cohesin-Based Partitioning Mechanism Revealed upon Transcriptional Inactivation of Centromere, in the Journal: (JOURNAL) of September/22,/2015
  • what: The authors demonstrate that these changes in viability are reflected in the concentration of the kinetochore protein Mif2 at CEN3 and in the level of sister centromere separation established in metaphase. The authors demonstrate the authors demonstrate that pericentromeric cohesion modulates the deleterious effects of GAL-CEN transcription and allows for greater . . .

     

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