A combined fragment-based virtual screening and std-nmr approach for the identi fi cation of e-cadherin ligands

HIGHLIGHTS

  • who: STD-NMR et al. from the Brunel University London, United Kingdom have published the Article: A combined fragment-based virtual screening and STD-NMR approach for the identi fi cation of E-cadherin ligands, in the Journal: (JOURNAL)
  • what: Targeting cadherin-cadherin interactions with ligands that are potentially able to inhibit or modulate their adhesive function Frontiers in Chemistry frontiersin.org 10.3389/fchem.2022.946087 following results: Maybridge Ro3 Diversity Fragment Library from 2,500 2D fragments to 4,290 3D structures, LifeChemicals PPI Fragment Library from 2,509 2D fragments to 6 . . .

     

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