A comparative pharmaco-metabolomic study of glutaminase inhibitors in glioma stem-like cells confirms biological effectiveness but reveals differences in target-specificity

HIGHLIGHTS

• who: Katharina Koch from the Glioma cell line , was generously provided by GRiggins (Baltimore, USA), by A. Vescovi (Milan, Italy), cell lines, , and , by M.S. Carro (Freiburg, Germany), cell line , by E. Raabe (Baltimore, USA), and cell line , (644) by C. HeroldMende (Heidelberg, Germany). GSC neurospheres were cultured in DMEM w/o pyruvate (Gibco, #11965092, Thermo Fisher Scientific, USA), % Ham's , Nutrient Mix (Gibco, #11765047), % , supplement (Gibco, #17504044), ng/ml human bFGF (Peprotech, #AF- B, USA), ng/ml human EGF (Peprotech, #AF-10015), µg/ml Heparin (Sigma, #H0878, Merck KGaA, Germany), and, × Anti-Anti (Gibco, #15240096 . . .
  

   

  

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