A comprehensive biomarker analysis of microsatellite unstable/mismatch repair deficient colorectal cancer cohort treated with immunotherapy

HIGHLIGHTS

  • who: Elena u00c9lez and colleagues from the , Barcelona, Spain Department of Pathology, d`Hebron University Hospital, Barcelona, Spain have published the Article: A Comprehensive Biomarker Analysis of Microsatellite Unstable/Mismatch Repair Deficient Colorectal Cancer Cohort Treated with Immunotherapy, in the Journal: (JOURNAL)
  • what: The authors show a molecular analysis of 16 MSI-H/dMMR mCRC patients treated with anti-PD-1/PD-L1 aiming to provide new insights into the immunotherapy biomarkers of response and resistance. When the authors focused on biallelic mutations, ARID1A was only found in IT-responders and, on the contrary, PTEN . . .

     

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